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Matches 1 - 50 out of 191

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Match	Document	Document Title
1	9012395	Treatment of extracellular matrix to reduce inflammation Pharmaceutical compositions are provided. The compositions comprise a compound comprising the hyaluronan-containing structure A-(low molecular weight hyaluronan domain)-B. The compositions also...
2	8999339	Methods for treating chronic obstructive pulmonary disease The present invention provides methods of treating a mammal having chronic obstructive pulmonary disease (COPD), independent of both smoking status and asthma status, with a therapeutically...
3	8993299	Polypeptides having cellobiohydrolase I activity and polynucleotides encoding same The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to...
4	8987191	Bioactive peptides and methods of using same Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
5	8986969	Polypeptides having cellobiohydrolase I activity and polynucleotides encoding same The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to...
6	8980266	Serpin fusion polypeptides and methods of use thereof This invention relates to molecules, particularly polypeptides, more particularly fusion proteins that include a serpin polypeptide or an amino acid sequence that is derived from a serpin and...
7	8980826	Method of treating chronic obstructive pulmonary disease The present invention relates to a method of promoting bronchodilation by administration of streptolysin O to a subject in need thereof.
8	8974794	C(epsilon)mX peptides for inducing immune responses to human mIgE on B lymphocytes The invention pertains to methods of using CεmX peptides (e.g., GLAGGSAQSQRAPDRVL; SEQ ID NO:2) that can bind effectively induce immune responses to membrane-bound IgE (mIgE) expressed on the...
9	8940686	Cytokine A novel cytokine, U83A, is described, as are variant forms of the cytokine, having a wide range of agonistic and antagonistic activity against chemokine receptors. Uses of the chemokine in...
10	8921306	Nociceptin mimetics The present invention relates to nociceptin peptide mimetics that have α-helical structures and bind to and modulate the opioid receptor-like-1 (ORL-1) receptor. The peptide mimetics are...
11	8916517	Analogs of pituitary adenylate cyclase-activating polypeptide (PACAP) and methods for their use This invention relates to novel analogs of pituitary adenylate cyclase-activating polypeptide (PACAP), which are agonists for the PACAP/vasoactive intestinal peptide (VIP) receptors: PAC1, VPAC1...
12	8912139	Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion Provided herein are peptide inhibitors of the interaction between End Binding Protein 3 (EB3) and Inositol 1,4,5-Trisphosphate Receptor Type 3 (IP3R3). Also provided are methods and materials for...
13	8852588	Treating allergic airway disorders using anti-IL-20 receptor antibodies Treatment of an allergic airway disorder (e.g., asthma or bronchial airway obstruction) using anti-IL-20R1 antibodies such as mAb51D, mAb7GW, or functional variants thereof.
14	8828926	Uses of natriuretic peptide constructs Use of constructs which bind to one or more natriuretic peptide receptors and include a plurality of amino acid residues and at least one amino acid surrogate of formula I: where R, R′, Q, Y, W,...
15	8828945	Inactivation of smooth muscle tissue Treatment and procedures for treating bodily conduits involves deactivating, killing, or otherwise treating smooth muscle tissue of the conduit.
16	8828394	Methods for treating IgE-mediated disorder This invention relates to methods of treating IgE mediated disorders such as allergy and asthma based on activating surface-bound IgD molecules on basophils. The invention also relates to methods...
17	8815809	Cysteine protease inhibitors Compounds of Formula II whereinR1a is H; and R1b is C1-C6alkyl, Carbocyclyl or Het; orR1a and R1b together define a saturated cyclic amine with 3-6 ring atoms;R2a and R2b are independently H,...
18	8796225	Regulation of immune responses by modulation of the function of antigen presenting cells The present invention relates to the use of chaperonin 10 to modulate the function of antigen presenting cells. More particularly the invention resides in the modulation of cell surface expression...
19	8785374	Inhibitors of mammalian tight junction opening The present invention provides novel peptides that inhibit and/or reduce the opening of mammalian tight junctions, i.e. peptide tight junction antagonists. The present invention also provides...
20	8765134	Methods for treating chronic obstructive pulmonary disease The present invention provides methods of treating a mammal having chronic obstructive pulmonary disease (COPD), independent of both smoking status and asthma status, with a therapeutically...
21	8754038	Template-fixed peptidomimetics with CCR10 antagonistic activity Novel template-fixed β-hairpin peptidomimetics of the general formula (I) wherein the single elements T or P are α-amino acid residues connected in either direction which, depending on their...
22	8741835	Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment A method and pharmaceutical composition for inhibiting the effect of glucocorticoids, particularly dexamethasone, which suppress growth hormone secretion, by administering ghrelin or a ghrelin...
23	8722618	IL4/IL13 binding repeat proteins and uses IL4/IL13-binding proteins comprise binding domains, which inhibit IL4/IL13 binding to IL4Ralpaha and common gamma chain complexes (Type 1) and inhibit IL4 binding to IL4Ralpha and IL13Ralpha1...
24	8679503	Methods, compositions and kits relating to chitnases and chitnase-like molecules and inflammation disease The present invention includes compositions and methods for the treatment of inflammatory disease (e.g., asthma, COPD, inflammatory bowel disease, atopic dermatitis, atopy, allergy, allergic...
25	8637452	Water soluble membrane proteins and methods for the preparation and use thereof The present invention is directed to water-soluble membrane proteins, methods for the preparation thereof and methods of use thereof.
26	8637453	Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain pyruvamide compounds of the following formula (for convenience, collectively...
27	8586037	Antibodies against IL-17BR The invention provides the antibody D9.2 and antibody molecules based on D9.2 which bind interleukin-17 receptor B. These may be useful in therapy, e.g. the treatment of asthma, ulcerative colitis...
28	8580260	Method of using anti-IL-13 antibodies The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related...
29	8569229	Compositions and methods which modulate G-protein signaling for the treatment of inflammatory disorders such as asthma and allergic conjunctivitis Compositions and methods for the treatment of asthma and inflammatory ocular disorders are disclosed.
30	8541363	Pyruvamide compounds as inhibitors of dust mite group 1 peptidase allergen and their use The present invention pertains generally to the field of therapeutic compounds and more specifically to certain pyruvamide compounds of the formula (X) (for convenience, collectively referred to...
31	8530407	Multi-component antioxidant compounds, pharmaceutical compositions containing same and their use for reducing or preventing oxidative stress An antioxidant compound is disclosed, along with pharmaceutical compositions and methods of treatment which utilize said compound. The compound is characterized by a peptide including at least...
32	8492329	Bioactive peptides and methods of using same Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
33	8470766	Protein kinase C therapy for the treatment of acute lung injury The present invention provides novel formulations of a δPKC inhibitor. The δPKC inhibitor can be, for example, a peptide. The present invention also discloses a method of preventing acute...
34	8440611	Analogues of neuropeptide Y having at least one synthetic amino acid substitution The present invention relates to novel analogues of neuropeptide Y, pharmaceutical compositions containing the same, pharmaceutical formulations containing the same, and method of treating...
35	8435517	Compositions and methods for treating IgE-mediated disorders The present invention relates to immunoglobulins that bind IgE and FcγRIIb with high affinity, said compositions being capable of inhibiting cells that express membrane-anchored IgE. Such...
36	8372799	Reverse protein A protein which is composed N-terminally of one or several C-terminal parts of the amino acid sequence of the mature tumor necrosis factor and C-terminally of one or several N-terminal parts of...
37	8371292	Use of ciclesonide for the treatment of respiratory diseases The invention relates to new method of treatment of respiratory diseases, in particular the treatment of asthmatic children.
38	8349793	Method for treatment of inflammatory disease and disorder The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. Exemplary modulators include inhibitors of PKC-alpha,...
39	8299019	Uses of modified ELR-CXC chemokine G31P to treat cancer Described herein is the use of a modified human chemokine, GS-CXCL8(3-72)K11R/G31P or G31P in the treatment of a number of cancers, including but by no means limited to prostate cancer, liver...
40	8298547	IgE CH3 peptide vaccine The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of...
41	8287866	Methods of treating IL-TIF associated inflammatory or immune diseases using antibodies against soluble zcytor 11 cytokine receptors Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zcytor11 receptors that may be used as novel cytokine...
42	8252741	Uses of modified ELR-CXC chemokine G31P Described herein is the use of a modified human chemokine, GS-CXCL8(3-73)K11R/G31P or G31P in the treatment of a number of diseases or disorders, including but by no means limited to pulmonary...
43	8221772	Pulmonary surfactant formulations and methods for promoting mucus clearance Methods and compositions to enhance mucus clearance and to treat pulmonary lung disorders such as cystic fibrosis are disclosed. The methods utilize compositions including synthetic pulmonary...
44	8138141	HMG1 antibody for treating inflammatory conditions There is disclosed a pharmaceutical composition and method for treating sepsis, including septic shock and ARDS (acute respiratory distress syndrome), comprising administering an effective amount...
45	8137701	Method of producing a dry earthworm powder Provided is a method of producing a dry earthworm powder without deterioration in useful pharmacological action, by removing dirt on the skin of earthworms while allowing the earthworms to excrete...
46	8114853	Methods of treating smooth muscle cell disorders The present invention provides methods of detecting cells showing smooth muscle differentiation. The present invention further provides methods of detecting tumor cells. The present invention...
47	8105571	Method of treating pulmonary disease with interferons A method of treating a pulmonary disease such as, for instance idiophathic pulmonary fibrosis (IPF), mixed connective tissue disease and asthma, comprising administering an aerosolized interferon...
48	8080249	Methods to treating chronic obstructive pulmonary disease The present invention provides methods of treating a mammal having chronic obstructive pulmonary disease (COPD), independent of both smoking status and asthma status/with a therapeutically...
49	8076281	Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment A method and pharmaceutical composition for inhibiting the effect of glucocorticoids, particularly dexamethasone, which suppress growth hormone secretion, by administering ghrelin or a ghrelin...
50	8071097	Apoptotic anti-IgE antibodies The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders.

Matches 1 - 50 out of 191

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